The Texas Cancer Research Biobank consisted of institutions across Texas, including:
Baylor College of Medicine (BCM) served as the coordinating center for the TCRB. The BCM team consisted of people from the Human Genome Sequencing Center (HGSC), the Dan L. Duncan Cancer Center, and the Center for Medical Ethics and Health Policy.
Baylor College of Medicine (BCM) and its affiliates headed efforts to develop standardized protocols and consents for the consortium, managed the biobank, performed DNA and RNA sequencing and specimen imaging, and developed software to maintain and share specimen and patient data.
TCRB Sample Sites
The following sample sites collected specimens and data from participating patients and sent them to the central processing, storage and sequencing facilities at BCM.
Ben Taub General Hospital is part of the Harris County Hospital District and provides patients with access to more than 40 medical specialties. Ben Taub has more than 26,000 adult and pediatric admissions and more than 184,000 specialty clinic visits.
Gradalis, Inc.® is a fully integrated biotechnology company based in Dallas, Texas, that focuses on development and manufacturing of drugs, vaccines, tools and diagnostics primarily for cancers.
Mary Crowley Cancer Research Centers is a non-profit organization based in Dallas, Texas, with seven clinical sites whose mission is to expand treatment options for all cancer patients through investigational vaccine, gene, and cellular therapies.
South Plains Oncology Consortium (SPOC) is a regional consortium devoted to conducting early phase oncology trials and translational cancer research. A major goal of SPOC is to improve access for new anti-cancer drugs to patients in West Texas and the surrounding region.
Texas Cancer Cell Repository (TXCCR) was a CPRIT-funded collaborative project between Texas Tech University Health Sciences Center School of Medicine Cancer Center at Lubbock, Texas and the University of Texas Southwestern Medical Center in Dallas, Texas. TXCCR developed and banked cell lines, and direct-to-mouse xenografts from tumor specimens to enable future biological and preclinical therapeutic studies.
Texas Children’s Hospital® is an internationally recognized full-care pediatric hospital located in the Texas Medical Center in Houston. One of the largest pediatric hospitals in the United States, Texas Children’s Hospital is dedicated to providing the finest possible pediatric patient care, education and research.